The second-half substitute, who has not scored since Boxing Day, won a 72nd-minute spot-kick with the Millers 3-1 down against the Addicks but the preceded to blaze over, effectively sending any hopes of a comeback high into the South Stand.
Clarke-Harris went for a repeat of his modus operandi for his successful penalty against Bristol City before Christmas, smashing it high and hard down the middle, but got this one painfully wrong.
Although knowing it was a crucial miss, Redfearn was not too harsh on his young striker.
"He held his hands up to be fair. He won the penalty himself, and I thought when he came on he was a real live wire to be fair, he put himself about so I don't want to be too critical of the lad.